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Life

Gene editing embryonic stem cells might increase risk of cancer

By Michael Le Page

11 June 2018

New Scientist. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

Embryonic stem cells hold much promise – but must be handled with care

Description:BSIP SA / Alamy Stock Photo

Embryonic stem cells could help treat all kinds of disorders, and editing the genomes of these stem cells could make the treatments far more potent. But there might be a catch.

A team at Novartis has found that genome editing kills most human embryonic stem cells – and that the ones that do survive are likely to have mutations in a key anti-cancer gene. Cells with such mutations are in theory far more likely to turn cancerous if implanted in the body.…

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