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Chemical cocktail could restore sight by regenerating optic nerves

The optic nerve has been partly regenerated in mice, raising hopes for treating blindness caused by conditions such as glaucoma

By Michael Le Page

16 February 2024

Glaucoma occurs when the optic nerve, which connects the eye to the brain, becomes damaged

Ian Miles / Alamy

The vision of mice with damaged optic nerves has been partly restored by generating new nerve cells in the eye to replace ones that died. The hope is this approach could help treat people with conditions that cause blindness by damaging the optic nerve, such as glaucoma.

“We can regenerate those cells,” says Biraj Mahato at the Children’s Hospital Los Angeles in California. But more studies in larger animals will have to be done before trials in people can be…

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