A popular video game could provide doctors with a way of diagnosing depression.
With some illnesses, such as diabetes, a simple test can usually quantify how severe a person’s condition is, but depression is more complicated. The condition has been linked to a shrunken hippocampus, a part of the brain that also plays a role in spatial memory, so Neda Gould at the US National Institute of Mental Health in Bethesda, Maryland, and her colleagues wondered whether a video game that tests spatial memory could help measure the severity of the illness.
To test their idea the researchers developed a game based on some scenes from Duke Nukem, a game in which players navigate around a virtual town. The participants, who were already familiar with the town, were asked to find their way to as many landmarks as possible within a set amount of time.
Depressed people found their way to an average of 2.4 locations compared with 3.8 locations for healthy controls. Indeed, the more depressed a person was, the lower the score (The American Journal of Psychiatry, vol 164, p 516). Gould hopes the test may eventually provide a quantifiable measure of depression.
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