Research into the biological basis of tiredness shows that both mental and
physical factors bring about that feeling of exhaustion. But where, when and
how in muscles and the nervous system does fatigue begin?
WE all know the feeling, yet the causes of fatigue have long proved hard to
identify. This is partly because the term “fatigue” can describe either
physical or mental states and partly because there are many contributing
factors. However all is not lost. Within the past few years, muscle
physiologists have traced the roots of physical fatigue to events that occur
within muscle cells. And although…
