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GOOD old-fashioned aspirin continues to surprise in an era of designer drugs
and big pharma. It turns out that large doses can reverse high blood sugar
levels in diabetic mice, opening up alternative routes for treating the
disease.

In humans, the equivalent dose would be 20 to 30 pills—far too high for
people to treat their own diabetes, warns researcher Steven Shoelson of the
Joslin Diabetes Center in Boston.

But the finding reveals that the inflammation pathways aspirin targets are
tightly linked to insulin resistance, one cause of type 2 diabetes. “Shoelson’s
is a very important discovery,” says Alan…

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