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Kill the healthy cells to strangle cancer

By Anil Ananthaswamy

9 November 2002

THE latest cancer vaccine has an unusual target. It attacks tumours by killing growing blood vessels, starving the cancers of blood.

Because it targets normal, healthy cells, cancers can’t evade its effects by mutating. And the same vaccine could be given to everyone, instead of having to be tailored to specific cancers. It might provide long-term protection from many cancers.

Trials of drugs that block the growth of the blood vessels that feed tumours have been disappointing. So Ralph Reisfeld and Andreas Niethammer of the Scripps Research Institute in La Jolla, California, created a vaccine to make the immune system…

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