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THE dengue fever virus can mutate much more rapidly than anyone thought, which could thwart the efforts of the teams rushing to create a vaccine.

Over the past few decades, the mosquito-borne virus has spread dramatically and now infects about 50 million people each year in tropical areas, killing at least 12,000. Two-fifths of the world’s population are at risk, and global warming will allow the virus to increase its range.

Developing an effective vaccine that protects against each of the four main types of the dengue virus has proved difficult. Now work by John Aaskov’s team at the…

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