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Death-defying cells mend broken hearts

By Peter Farley

16 August 2003

GENETIC engineering can keep adult stem cells alive long enough to repair damaged hearts. But it is not yet clear how the approach could be turned into a practical treatment for the millions who suffer heart attacks each year.

A few small trials on humans have already shown that injecting adult stem cells into the bloodstream after a bypass operation can produce some improvements in heart function (New Scientist, 11 January, p 14). But most of the cells die before they can do any good. Several animal experiments, says Victor Dzau of Harvard Medical School, have found that virtually…

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