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Doubt greets claims for artery-clearing drug

By Philip Cohen

15 November 2003

IS IT really possible to melt away the fat that gradually clogs up our arteries? That’s the claim that hit the headlines last week. But experts are treating the reports with caution.

In a study published last week, 47 people with heart disease were given five weekly injections of an experimental drug known as ETC-216. Other patients were injected with a placebo of salty water. At the end of the trial, the size of the fatty plaques clogging the arteries of the patients given ETC-216 had been reduced by an average of 4 per cent, reported Steven Nissen, the cardiologist…

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