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A MAGIC bullet that destroys the blood vessels that feed fat tissue could be just what obese people desperate to lose weight have been praying for. When the drug was given to overweight mice, they lost nearly a third of their body weight in a month.

Cancer drugs designed to inhibit blood vessel growth in tumours have already been shown to reduce fat levels in obese mice (New Scientist, 10 April, p 42), but there have been worries about their effect on other tissues. So Mikhail Kolonin of the University of Texas in Houston and his colleagues decided to…

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