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Gene therapy saves tissues from oxygen starvation

7 August 2004

DON’T leave treatments for stroke or heart attack until after the event – give those at high risk gene therapy in advance to protect them from the consequences.

This kind of intervention is being suggested by a team at Brigham and Women’s Hospital in Boston, and Queen’s University in Kingston, Ontario.

Lack of oxygen after a stroke or heart attack damages tissue. In response cells make proteins such as heme-oxygenase-1 (HO-1) to protect themselves. The problem is it normally takes the cells 6 to 12 hours to produce high enough levels of HO-1, by which time it is too late.

So…

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