A CANNABIS-LIKE substance produced by the brain may dampen delusional or psychotic experiences, rather than trigger them.
Heavy cannabis use has been linked to psychosis in the past, leading researchers to look for a connection between the brain’s natural cannabinoid system and schizophrenia. Sure enough, when Markus Leweke of the University of Cologne, Germany, and Andrea Giuffrida and Danielle Piomelli of the University of California, Irvine, looked at levels of the natural cannabis-like substance anandamide, they were higher in people with schizophrenia than in healthy controls.
The team measured levels of anandamide in the cerebrospinal fluid (CSF) of 47 people…
