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Gut reaction makes bad bugs worse

8 February 2006

ARMIES of pathogenic bacteria are toughened up in a mini “boot camp” when they are engulfed by protozoans in the guts of their bovine hosts.

The conventional view was that single-celled protozoans living in the guts of ruminants were benign, supplying the beasts with nutrients by digesting plant matter and bacteria before being digested themselves. Now a team at the National Animal Disease Center in Ames, Iowa, has revealed protozoans’ darker side.

The researchers collected protozoans from the stomachs of cattle and mixed them with a strain of salmonella that fends off digestion by protozoans. Calves fed salmonella that had…

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