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Time for bed, said the adrenal clock

31 May 2006

THE crocodile in Peter Pan had a ticking belly. We’ve got one too, except our ticking comes from the adrenal glands above our kidneys and not from a swallowed alarm clock.

The mammalian body clock was thought to be set exclusively by a part of the hypothalamus in the brain called the suprachiasmatic nucleus (SCN). Now Henryk Urbanski and his colleagues at the Oregon National Primate Research Center in Beaverton, Oregon, have discovered a second clock – in the adrenal glands.

Urbanski and his team discovered rhythmic 24-hour fluctuations in gene activity in at least 322 genes in the adrenal…

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