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Health

Pancreas fix reverses type 1 diabetes

By Linda Geddes

27 February 2008

Insulin-producing pancreas cells destroyed by type 1 diabetes may have been regenerated in mice, thanks to a new cocktail of drugs. The work, which effectively cures mice of the disease, provides insights into the early stages of diabetes and could open up new options for treatment.

Type 1 diabetes is an autoimmune disease marked by the loss of insulin-producing islet beta cells in the pancreas. The drug cocktail works by neutralising the immune system’s attack on the beta cells, as well as taming the inflammation that accompanies the disease.

“The drugs work by neutralising the immune system’s attack on pancreatic beta cells and by taming…

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