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Life

Early life could have relied on 'arsenic DNA'

By Michael Reilly

23 April 2008

A deadly poison, arsenic is best known for snuffing out life. But could it have played a key role in the origins of life on Earth?

Felisa Wolfe-Simon of Harvard University thinks so because the toxin behaves so similarly to phosphorus, an essential ingredient in nearly all living things. Much more arsenic would have been available in Earth’s primordial oceans than phosphorus. And while microbial activity was necessary later to unlock phosphorus from rocks, arsenic could have dissolved in water from hydrothermal vents.

Phosphorus binds to four oxygen atoms to form a negatively charged phosphate ion that is used to…

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