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Mice ascend Everest to combat doping in sport

28 May 2008

Edmund Hilary may have been the first man to conquer Everest but soon his feat will be repeated by a band of mice. As well as making history, the mice may reveal the natural biochemical changes that take place at high altitude, which could lead to a test for athletes who have had their genes manipulated.

High-altitude training benefits athletes by stimulating production of erythropoietin (EPO), a hormone that allows blood to carry more oxygen. Yet it is possible to cheat by artifically boosting EPO levels, either by taking supplements or maybe by manipulating athletes’ genes.

While today’s tests can…

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