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Health

Mixed results for Alzheimer's treatments

23 July 2008

WHAT a strange week for Alzheimer’s disease.

Rachelle Doody of Baylor College of Medicine in Houston, Texas, gave 120 patients Dimebon, an antihistamine drug, for a year. Their scores on practical cognitive ability tests rose significantly compared with those receiving a placebo, and their symptoms seemed to improve the longer they took the drug – a first for an Alzheimer’s drug (The Lancet, vol 372, p 207).

Yet in the same issue (p 216), a team led by Clive Holmes of the University of Southampton, UK, report that a vaccine that helps to destroy the protein plaques thought to…

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