DISAPPOINTING or what? The first whole genome sequencing of a pair of identical twins has uncovered little about the origins of disease – even though only one twin has multiple sclerosis (MS).
Identical twins inherit identical genomes but are exposed to different environmental influences. That means they can be enormously valuable in teasing apart genetic and environmental factors. But clearly even whole genome sequencing, the gold standard in genetics, has its limits, judging by the latest analysis from Sergio Baranzini of the University of California, San Francisco, and colleagues.
“Identical twins can be enormously valuable in teasing apart genetic and environmental factors”…
