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Health

Down's eyes are clue to Alzheimer's disease

26 May 2010

EYE tests could one day be used for the early detection of Alzheimer’s disease, thanks to the discovery of a link between the amount of a characteristic protein in the brain and levels of the same protein in the eye.

Virtually everyone with Down’s syndrome goes on to develop symptoms of Alzheimer’s. When Lee Goldstein of Boston University School of Medicine and colleagues examined lens and brain tissue during post-mortems of people with Down’s, they found that brain levels of amyloid protein correlated with those in the eye (PLoS One, DOI: 10.1371/journal.pone.0010659).

Clumps of amyloid protein in the brain…

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