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Muscle-based gene therapy beats HIV

By Andy Coghlan

30 November 2011

New Scientist. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

By bypassing the immune system altogether and turning muscles into antibody factories, mice are made invulnerable to HIV

(Image: MedialRF.com/Superstock.com)

Editorial:We can win the AIDS war with drugs and vaccines

HIV doesn’t play by the rules: instead of dodging the immune system it attacks it head on. Now it seems our best hope for a vaccine against the killer virus might also involve tearing up the rule book – by fighting an infection without help from the immune system.

Using this approach, mice can keep HIV at bay even when given 100 times the virus that would be needed to…

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