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Health

Antisense therapy promises to slow Huntington’s disease

13 December 2017

AN INCURABLE inherited illness that kills many of those affected by their 40s may be slowed by a novel drug injected into fluid surrounding the spine and brain.

Although the results of a trial in 46 people with Huntington’s disease in the UK, Germany and Canada were only preliminary, independent neurologists were still cautiously optimistic.

The drug is designed to stop production of the huntingtin protein, which is mutated in those with the condition and kills brain cells, causing gradual loss of mobility and brain activity.

Before it can be produced, the treatment intercepts and destroys RNA that carries the…

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