From David Jenkins, Carlton, Bedfordshire, UK
I read with interest the report that taking very high doses of vitamin C slows the progression of leukaemia in mice (26 August, p 18). Fifteen years ago, part of my treatment for acute promyelocytic leukaemia (APL) was a very high dose of all-trans retinoic acid. As I understand it, this is a metabolite of vitamin A and causes APL cells to differentiate and die.
I wonder whether it is worthwhile considering a possible role for other vitamins in cancer therapy and whether combinations of different vitamins may be more effective than high doses of single ones?
