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Is Alzheimer’s drug donanemab really a 'turning point' for treatment?

18 July 2023

The experimental drug donanemab slows the progression of Alzheimer's disease compared with a placebo, but the effect may not be large enough to be noticed by people with the condition or their families


Do new Alzheimer's drugs signal the end of the condition?

24 May 2023

Antibody treatments that target amyloid plaques in the brains of people with Alzheimer's have shown promise in trials, but questions about their side effects and practicality remain


Someone with Alzheimer's walks with his daughter in Yarumal, north of Antioquia department, Colombia in 2014

People with partial resistance to Alzheimer’s could inspire new drugs

15 May 2023

Researchers have identified two people from the same Colombian community with genes that both promote and prevent early onset Alzheimer's disease - a discovery that could lead to new treatments


New drug donanemab slows cognitive decline in early Alzheimer's

4 May 2023

The experimental treatment donanemab is now the second antibody drug to slow cognitive decline in people with early stage Alzheimer’s disease, but questions remain about its real-world benefits and safety


The brain may flush out its waste products after a mental workout

30 March 2023

A fluid-filled network that clears waste products from the brain may be important in neurological conditions, but we know little about how it works


alzheimer's disease with MRI; Shutterstock ID 1025800153; purchase_order: -; job: -; client: -; other: -

A new mitochondrial theory of Alzheimer's deserves serious attention

8 March 2023

A “grand unifying theory” of brain ageing suggests malfunctioning mitochondria might be to blame for Alzheimer’s and other brain conditions. And this new avenue of exploration already has some potential therapies at the ready


Observational studies suggest that puzzles may ward off dementia, but this has not been proven

Lifestyle may affect your dementia risk but the extent is exaggerated

18 January 2023

There are many things we can do to try to reduce our risk of dementia, but the condition is not usually preventable


Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer's disease

Alzheimer’s disease progression slowed using CRISPR technique in mice

12 December 2022

Removing only a small segment of a gene in the brain cells of mice reduced the formation of plaques seen in Alzheimer’s disease by 44 per cent


Alzheimer's may be caused by the accumulation of protein plaques and tangles in the brain

Alzheimer's drug lecanemab slows cognitive decline but concerns linger

30 November 2022

The drug lecanemab slowed the rate of cognitive decline among people with early Alzheimer's disease by 27 per cent, compared with placebo infusions, but some question if its potential safety concerns outweigh any benefits


alzheimer's disease on MRI; Shutterstock ID 677115010; purchase_order: -; job: -; client: -; other: -

Acid produced by the brain could drive disease-related psychosis

16 November 2022

Kynurenic acid is made in the brain and could play a role in psychosis related to schizophrenia, Alzheimer’s disease and bipolar disorder – and new drugs may be able to reduce it


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