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Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer's disease

Alzheimer’s disease progression slowed using CRISPR technique in mice

12 December 2022

Removing only a small segment of a gene in the brain cells of mice reduced the formation of plaques seen in Alzheimer’s disease by 44 per cent


Two Labrador puppies

Labrador dogs gene edited and cloned to prevent inherited hip disease

3 August 2022

CRISPR gene editing has been used to try to prevent a genetic disorder in dogs for the first time, in this case a common condition called hip dysplasia


Two beagle puppies

Gene-edited dogs created from cloned skin cells for the first time

22 July 2022

New gene-editing approach could be used to eliminate disease-causing mutations from pedigree dog breeds or even from clones of individual dogs


Illustration of the CRISPR-Cas9 gene editing complex

‘Softer’ form of CRISPR may edit genes more accurately

1 July 2022

Gene editing with CRISPR can cause off-target mutations, but this seems to happen less often with an enzyme that cuts one of the strands of DNA instead of both


DNA helix 3D illustration. Mutations under microscope. Decoding genome. Virtual modeling of chemical processes. Hi-tech in medicine; Shutterstock ID 1811660503; purchase_order: 020722; job: NS; client: NS; other:

What's next for the gene-edited children from CRISPR trial in China?

29 June 2022

Scientists in China are considering how best to look after three children who were gene-edited as embryos in He Jiankui’s controversial experiment


What is a genetically modified organism?

What is a genetically modified organism?

17 July 2020

A genetically modified organism (GMO) is usually defined as an organism whose DNA has been altered by genetic engineering.


Fiona Behan

How we're using CRISPR to fight cancer

2 December 2019

Molecular biologist Fiona Behan reports on how the CRISPR gene-editing technique can find cancer’s weak points, identifying targets for new drugs


Denis Rebrikov

Exclusive: Five couples lined up for CRISPR babies to avoid deafness

4 July 2019

Russian biologist Denis Rebrikov plans to help five couples who are deaf try CRISPR gene-editing to avoid having a child that inherits the condition


Genetics

Genetics

7 June 2019


Modified genes on DNA

Human genome editing is here – now we have to decide who is in charge

1 March 2019

The announcement of a WHO committee to discuss the scientific, ethical and legal issues surrounding human genome editing is to be welcomed, says Andy Greenfield


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